PrimePCR™ Probe Assay: LHB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0033866
Assay Design:   Exonic
Chromosome Location:   19:49519410-49519529question
Amplicon Length:   90
Splice Variants Targeted:   ENST00000221421 ENST00000391870

Gene Information

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq Jul 2008]

Gene Symbol:   LHB
Gene Name:   luteinizing hormone beta polypeptide
Aliases:   CGB4, LSH-B, hLHB
RefSeq:   NC_000019.9 NG_000019.3 NG_011464.1 NT_011109.16
Ensembl:   ENSG00000104826
Entrez:   3972
Chromosome Mapping:   19q13.32

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