PrimePCR™ Probe Assay: STX1A, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050391
Assay Design:   exonic
Chromosome Location:   7:73118684-73119500question
Amplicon Length:   61
Splice Variants Targeted:   ENST00000277657 ENST00000362006 ENST00000549621 ENST00000548278 ENST00000552495 ENST00000222812 ENST00000395156 ENST00000395154 ENST00000395155 ENST00000367159 ENST00000329800 ENST00000423166 ENST00000361714 ENST00000581324 ENST00000570347 ENST00000572494 ENST00000574942 ENST00000573948 ENST00000576203

Gene Information

This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3) and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq Sep 2009]

Gene Symbol:   STX1A
Gene Name:   syntaxin 1A (brain)
Aliases:   HPC-1, P35-1, STX1, SYN1A
RefSeq:   NC_000007.13 NT_007933.15 NG_013360.1
Ensembl:   ENSG00000106089
Entrez:   6804
Chromosome Mapping:   7q11.23

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