PrimePCR™ Probe Assay: TNFRSF18, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028021
Assay Design:   Intron-spanning
Chromosome Location:   1:1139817-1140864question
Amplicon Length:   135
Splice Variants Targeted:   ENST00000328596 ENST00000379268 ENST00000379265

Gene Information

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq Feb 2011]

Gene Symbol:   TNFRSF18
Gene Name:   tumor necrosis factor receptor superfamily, member 18
Aliases:   AITR, GITR, GITR-D
RefSeq:   NC_000001.10 NT_004350.19
Ensembl:   ENSG00000186891
Entrez:   8784
Chromosome Mapping:   1p36.3

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