PrimePCR™ Probe Assay: GZMB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029030
Assay Design:   Intron-spanning
Chromosome Location:   14:25102194-25103397question
Amplicon Length:   131
Splice Variants Targeted:   ENST00000415355 ENST00000216341 ENST00000526004 ENST00000382542 ENST00000382540

Gene Information

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize bind and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq Jul 2008]

Gene Symbol:   GZMB
Gene Name:   granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
Aliases:   CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000100453
Entrez:   3002
Chromosome Mapping:   14q11.2

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