PrimePCR™ Probe Assay: CCNE2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054360
Assay Design:   exonic
Chromosome Location:   8:95895113-95897411question
Amplicon Length:   95
Splice Variants Targeted:   ENST00000520509 ENST00000396133 ENST00000524224 ENST00000308108

Gene Information

The protein encoded by this gene belongs to the highly conserved cyclin family whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq Jul 2008]

Gene Symbol:   CCNE2
Gene Name:   cyclin E2
Aliases:   CYCE2
RefSeq:   NC_000008.10 NT_008046.16
Ensembl:   ENSG00000175305
Entrez:   9134
Chromosome Mapping:   8q22.1

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