Gene:  CCR5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes a member of the beta chemokine receptor family which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages and is known to be an important co-receptor for macrophage-tropic virus including HIV to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2) macrophage inflammatory protein 1 alpha (MIP-1 alpha) macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: CCR5, Human
chemokine (C-C motif) receptor 5

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0004411
Info:   Recommended - best efficiency
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PrimePCR™ SYBR® Green Assay: CCR5, Human
chemokine (C-C motif) receptor 5

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045912
Info:   Same primer pair as used in probe assay qHsaCEP0053173
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PrimePCR™ Probe Assay: CCR5, Human
chemokine (C-C motif) receptor 5

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053173
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