Gene:  LMNA, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability chromatin structure and gene expression. Vertebrate lamins consist of two types A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy familial partial lipodystrophy limb girdle muscular dystrophy dilated cardiomyopathy Charcot-Marie-Tooth disease and Hutchinson-Gilford progeria syndrome. [provided by RefSeq Apr 2012]

PrimePCR™ SYBR® Green Assay: LMNA, Human
lamin A/C

Assay Type: SYBR® Green
Assay Design: Exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0034112
Info:   Recommended - best efficiency
List Price:    $174.00
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PrimePCR™ SYBR® Green Assay: LMNA, Human
lamin A/C

Assay Type: SYBR® Green
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCED0045911
Info:   Same primer pair as used in probe assay qHsaCEP0053172
List Price:    $174.00
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PrimePCR™ Probe Assay: LMNA, Human
lamin A/C

Assay Type: Probe
Assay Design: exonic
Application: Gene Expression
Unique Assay ID: qHsaCEP0053172
List Price:    $255.00
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