PrimePCR™ Probe Assay: CXCL11, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CXCL11, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CXCL11, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0024091
Assay Design:   Exonic
Chromosome Location:   4:76957080-76957232question
Amplicon Length:   123
Splice Variants Targeted:   ENST00000306621 ENST00000503860

Gene Information

Chemokines are a group of small (approximately 8 to 14 kD) mostly basic structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane G protein-coupled receptors. Chemokines also play fundamental roles in the development homeostasis and function of the immune system and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies CXC and CC. This gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CXCL11
Gene Name:   chemokine (C-X-C motif) ligand 11
Aliases:   H174, I-TAC, IP-9, IP9, MGC102770, SCYB11, SCYB9B, b-R1
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000169248
Entrez:   6373
Chromosome Mapping:   4q21.2

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