PrimePCR™ Probe Assay: BIRC5, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: BIRC5, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: BIRC5, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0024115
Assay Design:   Exonic
Chromosome Location:   17:76219978-76220107question
Amplicon Length:   100
Splice Variants Targeted:   ENST00000374948 ENST00000301633 ENST00000350051

Gene Information

This gene is a member of the inhibitor of apoptosis (IAP) gene family which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq Jun 2011]

Gene Symbol:   BIRC5
Gene Name:   baculoviral IAP repeat containing 5
Aliases:   API4, EPR-1
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000089685
Entrez:   332
Chromosome Mapping:   17q25

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