PrimePCR™ Probe Assay: BID, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049260
Assay Design:   exonic
Chromosome Location:   22:18218357-18220880question
Amplicon Length:   69
Splice Variants Targeted:   ENST00000317361 ENST00000399774 ENST00000399765 ENST00000342111 ENST00000551952 ENST00000399767

Gene Information

This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found but the full-length nature of some variants has not been defined. [provided by RefSeq Jul 2008]

Gene Symbol:   BID
Gene Name:   BH3 interacting domain death agonist
Aliases:   FP497, MGC15319, MGC42355
RefSeq:   NC_000022.10 NT_011519.10
Ensembl:   ENSG00000015475
Entrez:   637
Chromosome Mapping:   22q11.1

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