PrimePCR™ Probe Assay: GRB14, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: GRB14, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: GRB14, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050856
Assay Design:   exonic
Chromosome Location:   2:165404227-165404321question
Amplicon Length:   65
Splice Variants Targeted:   ENST00000263915 ENST00000446413 ENST00000424693 ENST00000543549

Gene Information

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and in particular on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene but their full-length natures have not been determined to date. [provided by RefSeq Jul 2008]

Gene Symbol:   GRB14
Gene Name:   growth factor receptor-bound protein 14
Aliases:   Not Available
RefSeq:   NC_000002.11 NT_005403.17
Ensembl:   ENSG00000115290
Entrez:   2888
Chromosome Mapping:   2q22-q24

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