PrimePCR™ Probe Assay: PML, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
Your Price:   Log In
 

Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052226
Assay Design:   exonic
Chromosome Location:   15:74290601-74290793question
Amplicon Length:   163
Splice Variants Targeted:   ENST00000395135 ENST00000395132 ENST00000268059 ENST00000354026 ENST00000268058 ENST00000565898 ENST00000569477 ENST00000569965 ENST00000567543 ENST00000436891 ENST00000435786 ENST00000564428 ENST00000359928 ENST00000563500

Gene Information

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains a RING a B-box type 1 and a B-box type 2 and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Jul 2008]

Gene Symbol:   PML
Gene Name:   promyelocytic leukemia
Aliases:   MYL, PP8675, RNF71, TRIM19
RefSeq:   NC_000015.9 NT_010194.17
Ensembl:   ENSG00000140464
Entrez:   5371
Chromosome Mapping:   15q22

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined