PrimePCR™ Probe Assay: NCOR2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: NCOR2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: NCOR2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055351
Assay Design:   exonic
Chromosome Location:   12:124957662-124968267question
Amplicon Length:   112
Splice Variants Targeted:   ENST00000405201 ENST00000404621 ENST00000429285 ENST00000458234 ENST00000420698 ENST00000542927 ENST00000448008 ENST00000356219 ENST00000397355 ENST00000404121 ENST00000537098 ENST00000539778 ENST00000398040

Gene Information

This gene encodes a nuclear receptor co-repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone- and retinoic acid receptor-associated co-repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant expression of this gene is associated with certain cancers. Alternate splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq Apr 2011]

Gene Symbol:   NCOR2
Gene Name:   nuclear receptor corepressor 2
Aliases:   CTG26, FLJ25011, N-CoR2, SMAP270, SMRT, SMRTE, SMRTE-tau, TNRC14, TRAC, TRAC-1, TRAC1
RefSeq:   NC_000012.11 NT_009755.19 NG_022928.1
Ensembl:   ENSG00000196498
Entrez:   9612
Chromosome Mapping:   12q24

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