PrimePCR™ Probe Assay: RUNX3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028433
Assay Design:   Intron-spanning
Chromosome Location:   1:25245746-25254144question
Amplicon Length:   140
Splice Variants Targeted:   ENST00000308873 ENST00000338888 ENST00000399916 ENST00000428150 ENST00000540420

Gene Information

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   RUNX3
Gene Name:   runt-related transcription factor 3
Aliases:   AML2, CBFA3, FLJ34510, MGC16070, PEBP2aC
RefSeq:   NC_000001.10 NT_004610.19
Ensembl:   ENSG00000020633
Entrez:   864
Chromosome Mapping:   1p36

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