PrimePCR™ Probe Assay: LEPR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
Your Price:   Log In
 

Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031759
Assay Design:   Intron-spanning
Chromosome Location:   1:66036364-66038047question
Amplicon Length:   131
Splice Variants Targeted:   ENST00000349533 ENST00000371060 ENST00000371059 ENST00000371058 ENST00000344610 ENST00000406510

Gene Information

The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight) and is involved in the regulation of fat metabolism as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons however encode distinct proteins (PMID:9207021).[provided by RefSeq Nov 2010]

Gene Symbol:   LEPR
Gene Name:   leptin receptor
Aliases:   CD295, DKFZp686B1731, OBR
RefSeq:   NC_000001.10 NT_032977.9 NG_015831.1
Ensembl:   ENSG00000116678
Entrez:   3953
Chromosome Mapping:   1p31

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined