PrimePCR™ Probe Assay: RAPGEF2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031966
Assay Design:   Intron-spanning
Chromosome Location:   4:160225548-160235809question
Amplicon Length:   115
Splice Variants Targeted:   ENST00000505478 ENST00000511336 ENST00000510510 ENST00000264431 ENST00000514565

Gene Information

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs) such as RAPGEF2 serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al. 2000 [PubMed 10934204]).[supplied by OMIM Mar 2008]

Gene Symbol:   RAPGEF2
Gene Name:   Rap guanine nucleotide exchange factor (GEF) 2
Aliases:   CNrasGEF, NRAPGEP, PDZ-GEF1, PDZGEF1, RA-GEF, Rap-GEP, nRap GEP
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000109756
Entrez:   9693
Chromosome Mapping:   4q32.1

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