PrimePCR™ Probe Assay: CD70, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0041410
Assay Design:   Intron-spanning
Chromosome Location:   19:6586361-6590876question
Amplicon Length:   85
Splice Variants Targeted:   ENST00000379803 ENST00000248054 ENST00000284486 ENST00000534308 ENST00000528897 ENST00000598234 ENST00000344649 ENST00000423145 ENST00000245903

Gene Information

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated but not on resting T and B lymphocytes. It induces proliferation of costimulated T cells enhances the generation of cytolytic T cells and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation cytotoxic function of natural killer cells and immunoglobulin sythesis. [provided by RefSeq Jul 2008]

Gene Symbol:   CD70
Gene Name:   CD70 molecule
Aliases:   CD27L, CD27LG, TNFSF7
RefSeq:   NC_000019.9 NT_011255.14
Ensembl:   ENSG00000125726
Entrez:   970
Chromosome Mapping:   19p13

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