PrimePCR™ Probe Assay: EFNA5, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0023977
Assay Design:   Exonic
Chromosome Location:   5:106763012-106763130question
Amplicon Length:   89
Splice Variants Targeted:   ENST00000333274 ENST00000509503

Gene Information

Ephrin-A5 a member of the ephrin gene family prevents axon bundling in cocultures of cortical neurons with astrocytes a model of late stage nervous system development and differentiation. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events particularly in the nervous system. EPH receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships ephrins are divided into the ephrin-A (EFNA) class which are anchored to the membrane by a glycosylphosphatidylinositol linkage and the ephrin-B (EFNB) class which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. [provided by RefSeq Jul 2008]

Gene Symbol:   EFNA5
Gene Name:   ephrin-A5
Aliases:   AF1, EFL5, EPLG7, GLC1M, LERK7, RAGS
RefSeq:   NC_000005.9 NT_034772.6
Ensembl:   ENSG00000184349
Entrez:   1946
Chromosome Mapping:   5q21

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