PrimePCR™ Probe Assay: KRIT1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
Your Price:   Log In
 

Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039007
Assay Design:   exonic
Chromosome Location:   7:91874298-91874430question
Amplicon Length:   103
Splice Variants Targeted:   ENST00000340022 ENST00000412043 ENST00000394505 ENST00000394503 ENST00000458177 ENST00000454017 ENST00000413688 ENST00000458493 ENST00000425919 ENST00000444960 ENST00000422347 ENST00000425073 ENST00000394507

Gene Information

This gene encodes a protein containing four ankyrin repeats a band 4.1/ezrin/radixin/moesin (FERM) domain and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha) and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A) which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Sep 2009]

Gene Symbol:   KRIT1
Gene Name:   KRIT1, ankyrin repeat containing
Aliases:   CAM, CCM1
RefSeq:   NC_000007.13 NT_007933.15 NG_012964.1
Ensembl:   ENSG00000001631
Entrez:   889
Chromosome Mapping:   7q21.2

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined