PrimePCR™ Probe Assay: NFKBIB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040370
Assay Design:   exonic
Chromosome Location:   19:39396054-39396160question
Amplicon Length:   77
Splice Variants Targeted:   ENST00000576510 ENST00000572515 ENST00000575359 ENST00000313582 ENST00000392079

Gene Information

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family which inhibit NF-kappa-B by complexing with and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway thereby allowing activation of the NF-kappa-B which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq Jul 2011]

Gene Symbol:   NFKBIB
Gene Name:   nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
Aliases:   IKBB, TRIP9
RefSeq:   NC_000019.9 NT_011109.16
Ensembl:   ENSG00000104825
Entrez:   4793
Chromosome Mapping:   19q13.1

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