PrimePCR™ Probe Assay: OCLN, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041012
Assay Design:   exonic
Chromosome Location:   5:68843809-68847382question
Amplicon Length:   101
Splice Variants Targeted:   ENST00000574259 ENST00000572261 ENST00000355237 ENST00000396442 ENST00000380766 ENST00000538151 ENST00000542132

Gene Information

This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG) an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq Apr 2011]

Gene Symbol:   OCLN
Gene Name:   occludin
Aliases:   BLCPMG, FLJ08163, FLJ18079, FLJ77961, FLJ94056, MGC34277
RefSeq:   NC_000005.9 NT_006713.15 NW_003315917.1
Ensembl:   ENSG00000197822
Entrez:   100506658
Chromosome Mapping:   5q13.1

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