PrimePCR™ Probe Assay: GSTM2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0041083
Assay Design:   exonic
Chromosome Location:   1:110214104-110217372question
Amplicon Length:   75
Splice Variants Targeted:   ENST00000369836 ENST00000326729 ENST00000369833 ENST00000336075 ENST00000369831 ENST00000460717 ENST00000241337 ENST00000414179 ENST00000369829 ENST00000442650 ENST00000309851 ENST00000369823 ENST00000256593 ENST00000369813 ENST00000369812 ENST00000549687 ENST00000548392 ENST00000360820

Gene Information

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha kappa mu omega pi sigma theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds including carcinogens therapeutic drugs environmental toxins and products of oxidative stress by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq Jul 2008]

Gene Symbol:   GSTM2
Gene Name:   glutathione S-transferase mu 2 (muscle)
Aliases:   GST4, GSTM, GSTM2-2, GTHMUS, MGC117303
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000213366
Entrez:   2946
Chromosome Mapping:   1p13.3

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