PrimePCR™ Probe Assay: DPYSL2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049930
Assay Design:   exonic
Chromosome Location:   8:26439573-26441460question
Amplicon Length:   117
Splice Variants Targeted:   ENST00000521913 ENST00000493789 ENST00000311151 ENST00000522745 ENST00000523027

Gene Information

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Sep 2011]

Gene Symbol:   DPYSL2
Gene Name:   dihydropyrimidinase-like 2
Aliases:   CRMP2, DHPRP2, DRP-2, DRP2
RefSeq:   NC_000008.10 NT_167187.1
Ensembl:   ENSG00000092964
Entrez:   1808
Chromosome Mapping:   8p22-p21

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