PrimePCR™ Probe Assay: NEFH, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050026
Assay Design:   exonic
Chromosome Location:   22:29886889-29886993question
Amplicon Length:   75
Splice Variants Targeted:   ENST00000310624

Gene Information

Neurofilaments are type IV intermediate filament heteropolymers composed of light medium and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq Oct 2008]

Gene Symbol:   NEFH
Gene Name:   neurofilament, heavy polypeptide
Aliases:   NFH
RefSeq:   NC_000022.10 NG_008404.1 NT_011520.12
Ensembl:   ENSG00000100285
Entrez:   4744
Chromosome Mapping:   22q12.2

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