PrimePCR™ Probe Assay: SLC9A3R1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050521
Assay Design:   exonic
Chromosome Location:   17:72765284-72765404question
Amplicon Length:   91
Splice Variants Targeted:   ENST00000262613 ENST00000413388

Gene Information

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles microvilli and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2 and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq Sep 2009]

Gene Symbol:   SLC9A3R1
Gene Name:   solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
Aliases:   EBP50, NHERF, NHERF1, NPHLOP2
RefSeq:   NC_000017.10 NG_013022.1 NT_010783.15
Ensembl:   ENSG00000109062
Entrez:   9368
Chromosome Mapping:   17q25.1

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