PrimePCR™ Probe Assay: CCND3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050708
Assay Design:   exonic
Chromosome Location:   6:41905027-41905121question
Amplicon Length:   65
Splice Variants Targeted:   ENST00000372991 ENST00000511642 ENST00000372987 ENST00000415497 ENST00000372988 ENST00000414200 ENST00000510503 ENST00000512426 ENST00000508143 ENST00000505064

Gene Information

The protein encoded by this gene belongs to the highly conserved cyclin family whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6 whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2008]

Gene Symbol:   CCND3
Gene Name:   cyclin D3
Aliases:   Not Available
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000112576
Entrez:   896
Chromosome Mapping:   6p21

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