PrimePCR™ Probe Assay: CTNND2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053927
Assay Design:   exonic
Chromosome Location:   5:11397310-11411752question
Amplicon Length:   81
Splice Variants Targeted:   ENST00000304623 ENST00000511377 ENST00000503622 ENST00000502551 ENST00000513598 ENST00000508761 ENST00000359640 ENST00000458100

Gene Information

This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome.[provided by RefSeq Aug 2010]

Gene Symbol:   CTNND2
Gene Name:   catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
Aliases:   GT24, NPRAP
RefSeq:   NC_000005.9 NG_023544.1 NT_006576.16
Ensembl:   ENSG00000169862
Entrez:   1501
Chromosome Mapping:   5p15.2

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