PrimePCR™ Probe Assay: SPHK1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0057678
Assay Design:   exonic
Chromosome Location:   17:74383045-74383194question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000545180 ENST00000592299 ENST00000590959 ENST00000323374 ENST00000392496

Gene Information

The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P) a lipid mediator with both intra- and extracellular functions. Intracellularly S1P regulates proliferation and survival and extracellularly it is a ligand for cell surface G protein-coupled receptors. This protein and its product S1P play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory antiapoptotic and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Sep 2011]

Gene Symbol:   SPHK1
Gene Name:   sphingosine kinase 1
Aliases:   SPHK
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000176170
Entrez:   8877
Chromosome Mapping:   17q25.2

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