PrimePCR™ Probe Assay: EPS15, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: EPS15, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: EPS15, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058155
Assay Design:   exonic
Chromosome Location:   1:51873991-51875294question
Amplicon Length:   72
Splice Variants Targeted:   ENST00000371730 ENST00000371733 ENST00000396122

Gene Information

This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq May 2009]

Gene Symbol:   EPS15
Gene Name:   epidermal growth factor receptor pathway substrate 15
Aliases:   AF-1P, AF1P, MLLT5
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000085832
Entrez:   2060
Chromosome Mapping:   1p32

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