PrimePCR™ Probe Assay: MGLL, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058399
Assay Design:   exonic
Chromosome Location:   3:127411053-127413824question
Amplicon Length:   91
Splice Variants Targeted:   ENST00000434178 ENST00000496306 ENST00000487473 ENST00000398101 ENST00000484451 ENST00000265052 ENST00000453507 ENST00000398104

Gene Information

This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Feb 2012]

Gene Symbol:   MGLL
Gene Name:   monoglyceride lipase
Aliases:   HU-K5, HUK5, MAGL, MGL
RefSeq:   NC_000003.11 NT_005612.16
Ensembl:   ENSG00000074416
Entrez:   11343
Chromosome Mapping:   3q21.3

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