PrimePCR™ SYBR® Green Assay: CYBB, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0029732

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0015139
Assay Design:   Intron-spanning
Chromosome Location:   X:37660517-37663174question
Amplicon Length:   100
Splice Variants Targeted:   ENST00000378588 ENST00000545017 ENST00000536160

Gene Information

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq Jul 2008]

Gene Symbol:   CYBB
Gene Name:   cytochrome b-245, beta polypeptide
Aliases:   CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
RefSeq:   NC_000023.10 NG_009065.1 NT_079573.4
Ensembl:   ENSG00000165168
Entrez:   1536
Chromosome Mapping:   Xp21.1

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