PrimePCR™ Probe Assay: ADRBK1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026332
Assay Design:   Intron-spanning
Chromosome Location:   11:67044743-67046914question
Amplicon Length:   146
Splice Variants Targeted:   ENST00000308595 ENST00000526285

Gene Information

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq Jul 2008]

Gene Symbol:   ADRBK1
Gene Name:   adrenergic, beta, receptor kinase 1
Aliases:   BARK1, BETA-ARK1, FLJ16718, GRK2
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000173020
Entrez:   156
Chromosome Mapping:   11q13.1

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