PrimePCR™ Probe Assay: AC008810.1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: AC008810.1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: AC008810.1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026520
Assay Design:   Intron-spanning
Chromosome Location:   5:40777600-40798244question
Amplicon Length:   139
Splice Variants Targeted:   ENST00000397128 ENST00000354209 ENST00000296800

Gene Information

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq Jul 2008]

Gene Symbol:   AC008810.1
Gene Name:   5'-AMP-activated protein kinase catalytic subunit alpha-1
Aliases:   AMPK, AMPKa1, MGC33776, MGC57364
RefSeq:   NC_000005.9 NT_006576.16
Ensembl:   ENSG00000132356
Entrez:   5562
Chromosome Mapping:   5p12

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