PrimePCR™ Probe Assay: LRP8, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026938
Assay Design:   Intron-spanning
Chromosome Location:   1:53730046-53732281question
Amplicon Length:   130
Splice Variants Targeted:   ENST00000306052 ENST00000371454 ENST00000465675 ENST00000354412 ENST00000347547 ENST00000475501

Gene Information

This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Jun 2011]

Gene Symbol:   LRP8
Gene Name:   low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Aliases:   APOER2, HSZ75190, MCI1
RefSeq:   NC_000001.10 NT_032977.9 NG_011517.1
Ensembl:   ENSG00000157193
Entrez:   7804
Chromosome Mapping:   1p34

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