PrimePCR™ Probe Assay: YWHAQ, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027129
Assay Design:   Intron-spanning
Chromosome Location:   2:9725442-9728306question
Amplicon Length:   111
Splice Variants Targeted:   ENST00000238081 ENST00000381844 ENST00000539979

Gene Information

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic however there is no correlation between the repeat number and the disease. [provided by RefSeq Jul 2008]

Gene Symbol:   YWHAQ
Gene Name:   tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Aliases:   14-3-3, 1C5, HS1
RefSeq:   NC_000002.11 NT_005334.16
Ensembl:   ENSG00000134308
Entrez:   10971
Chromosome Mapping:   2p25.1

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