PrimePCR™ Probe Assay: TGFBR3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027145
Assay Design:   Intron-spanning
Chromosome Location:   1:92182162-92184896question
Amplicon Length:   102
Splice Variants Targeted:   ENST00000370399 ENST00000525962 ENST00000465892 ENST00000212355

Gene Information

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3 which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq Sep 2010]

Gene Symbol:   TGFBR3
Gene Name:   transforming growth factor, beta receptor III
Aliases:   BGCAN, betaglycan
RefSeq:   NG_027757.1 NC_000001.10 NT_032977.9
Ensembl:   ENSG00000069702
Entrez:   7049
Chromosome Mapping:   1p33-p32

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