PrimePCR™ Probe Assay: FBXO5, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027829
Assay Design:   Intron-spanning
Chromosome Location:   6:153292474-153293480question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000229758 ENST00000367241

Gene Information

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box) which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains Fbls containing leucine-rich repeats and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. This protein is similar to xenopus early mitotic inhibitor-1 (Emi1) which is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Dec 2008]

Gene Symbol:   FBXO5
Gene Name:   F-box protein 5
Aliases:   EMI1, FBX5, Fbxo31
RefSeq:   NC_000006.11 NT_025741.15
Ensembl:   ENSG00000112029
Entrez:   26271
Chromosome Mapping:   6q25.2

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