PrimePCR™ Probe Assay: SRF, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0029584
Assay Design:   Intron-spanning
Chromosome Location:   6:43141747-43143518question
Amplicon Length:   150
Splice Variants Targeted:   ENST00000265354 ENST00000457278

Gene Information

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1 Agamous Deficiens and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes for example c-fos and thereby participates in cell cycle regulation apoptosis cell growth and cell differentiation. This gene is the downstream target of many pathways; for example the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq Jul 2008]

Gene Symbol:   SRF
Gene Name:   serum response factor (c-fos serum response element-binding transcription factor)
Aliases:   MCM1
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000112658
Entrez:   6722
Chromosome Mapping:   6p21.1

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