PrimePCR™ Probe Assay: RASA3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030094
Assay Design:   Intron-spanning
Chromosome Location:   13:114786891-114789811question
Amplicon Length:   121
Splice Variants Targeted:   ENST00000334062 ENST00000389544 ENST00000542651

Gene Information

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1345-tetrakisphosphate-binding protein like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains with this particular member having a domain consistent with its localization to the plasma membrane. [provided by RefSeq Jul 2008]

Gene Symbol:   RASA3
Gene Name:   RAS p21 protein activator 3
Aliases:   GAP1IP4BP, GAPIII, MGC46517, MGC47588
RefSeq:   NC_000013.10 NT_024498.12
Ensembl:   ENSG00000185989
Entrez:   22821
Chromosome Mapping:   13q34

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