PrimePCR™ Probe Assay: TRAP1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TRAP1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TRAP1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030121
Assay Design:   Intron-spanning
Chromosome Location:   16:3722768-3724408question
Amplicon Length:   93
Splice Variants Targeted:   ENST00000246957 ENST00000538171

Gene Information

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction protein folding protein degradation and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1; MIM 140571) and endoplasmic reticulum (HSP90B1; MIM 191175) (Chen et al. 2005 [PubMed 16269234]).[supplied by OMIM Aug 2008]

Gene Symbol:   TRAP1
Gene Name:   TNF receptor-associated protein 1
Aliases:   HSP75, HSP90L
RefSeq:   NC_000016.9 NG_009285.1 NT_010393.16
Ensembl:   ENSG00000126602
Entrez:   10131
Chromosome Mapping:   16p13.3

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