PrimePCR™ Probe Assay: CFTR, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0031790
Assay Design:   Intron-spanning
Chromosome Location:   7:117254685-117267641question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000003084 ENST00000426809 ENST00000468795 ENST00000454343

Gene Information

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described many of which result from mutations in this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CFTR
Gene Name:   cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
Aliases:   ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1
RefSeq:   NC_000007.13 NG_016465.1 NT_007933.15
Ensembl:   ENSG00000001626
Entrez:   1080
Chromosome Mapping:   7q31.2

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