PrimePCR™ Probe Assay: RPS6, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0040774
Assay Design:   Intron-spanning
Chromosome Location:   9:19376590-19378439question
Amplicon Length:   104
Splice Variants Targeted:   ENST00000380394 ENST00000380384 ENST00000315377

Gene Information

Ribosomes the organelles that catalyze protein synthesis consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli including growth factors tumor-promoting agents and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq Jul 2008]

Gene Symbol:   RPS6
Gene Name:   ribosomal protein S6
Aliases:   S6
RefSeq:   NC_000009.11 NT_008413.18
Ensembl:   ENSG00000137154
Entrez:   6194
Chromosome Mapping:   9p21

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