PrimePCR™ Probe Assay: TRPC6, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0035501
Assay Design:   Exonic
Chromosome Location:   11:101454065-101454174question
Amplicon Length:   80
Splice Variants Targeted:   ENST00000344327 ENST00000532133 ENST00000348423 ENST00000360497

Gene Information

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq Mar 2009]

Gene Symbol:   TRPC6
Gene Name:   transient receptor potential cation channel, subfamily C, member 6
Aliases:   FLJ11098, FLJ14863, FSGS2, TRP6
RefSeq:   NC_000011.9 NG_011476.1 NT_033899.8
Ensembl:   ENSG00000137672
Entrez:   7225
Chromosome Mapping:   11q22.1

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