PrimePCR™ Probe Assay: CTSD, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CTSD, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CTSD, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051022
Assay Design:   exonic
Chromosome Location:   11:1780239-1780762question
Amplicon Length:   66
Splice Variants Targeted:   ENST00000367196 ENST00000438213 ENST00000236671

Gene Information

This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains both produced from a single protein precursor. This proteinase which is a member of the peptidase C1 family has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases including breast cancer and possibly Alzheimer disease. [provided by RefSeq Jul 2008]

Gene Symbol:   CTSD
Gene Name:   cathepsin D
Aliases:   CLN10, CPSD, MGC2311
RefSeq:   NC_000011.9 NG_008655.1 NT_009237.18
Ensembl:   ENSG00000117984
Entrez:   1509
Chromosome Mapping:   11p15.5

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