PrimePCR™ Probe Assay: PTPRE, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PTPRE, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PTPRE, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0033745
Assay Design:   Intron-spanning
Chromosome Location:   10:129861394-129866396question
Amplicon Length:   150
Splice Variants Targeted:   ENST00000254667 ENST00000306042 ENST00000439034 ENST00000419012 ENST00000430713

Gene Information

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitotic cycle and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported one of which encodes a receptor-type PTP that possesses a short extracellular domain a single transmembrane region and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways cytokines induced SATA signaling as well as the activation of voltage-gated K+ channels. [provided by RefSeq Jul 2008]

Gene Symbol:   PTPRE
Gene Name:   protein tyrosine phosphatase, receptor type, E
Aliases:   DKFZp313F1310, FLJ57799, FLJ58245, HPTPE, PTPE, R-PTP-EPSILON
RefSeq:   NC_000010.10 NT_008818.16
Ensembl:   ENSG00000132334
Entrez:   5791
Chromosome Mapping:   10q26

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