PrimePCR™ Probe Assay: MGST1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0057878
Assay Design:   Intron-spanning
Chromosome Location:   12:16507253-16516733question
Amplicon Length:   130
Splice Variants Targeted:   ENST00000536371 ENST00000396210 ENST00000535309 ENST00000540126 ENST00000396207 ENST00000010404 ENST00000396209

Gene Information

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins two of which are involved in the production of leukotrienes and prostaglandin E important mediators of inflammation. Other family members demonstrating glutathione S-transferase and peroxidase activities are involved in cellular defense against toxic carcinogenic and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress. Four transcript variants of this gene encode one protein isoform. [provided by RefSeq Jul 2008]

Gene Symbol:   MGST1
Gene Name:   microsomal glutathione S-transferase 1
Aliases:   GST12, MGC14525, MGST, MGST-I
RefSeq:   NC_000012.11 NT_009714.17
Ensembl:   ENSG00000008394
Entrez:   4257
Chromosome Mapping:   12p12.3-p12.1

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