Gene:  Myc, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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The protein encoded by this gene is a multifunctional nuclear phosphoprotein that plays a role in cell cycle progression apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations overexpression rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors leukemias and lymphomas including Burkitt lymphoma in human. There is evidence to show that alternative translation initiations from an upstream in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini in human and mouse. Under conditions of stress such as high cell densities and methionine deprivation there is a specific and dramatic increase in the synthesis of the non-AUG initiated protein suggesting its importance in times of adversity. Alternative splicing results in multiple transcript variants. [provided by RefSeq Apr 2010]

PrimePCR™ SYBR® Green Assay: Myc, Rat
Myc proto-oncogene protein

Assay Type: SYBR® Green
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qRnoCID0007760
List Price:    $174.00
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PrimePCR™ Probe Assay: Myc, Rat
Myc proto-oncogene protein

Assay Type: Probe
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qRnoCIP0029591
List Price:    $255.00
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