PrimePCR™ Probe Assay: CHRM2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: CHRM2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: CHRM2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0035618
Assay Design:   Exonic
Chromosome Location:   7:136699854-136699995question
Amplicon Length:   112
Splice Variants Targeted:   ENST00000445907 ENST00000320658 ENST00000453373 ENST00000401861 ENST00000397608 ENST00000402486

Gene Information

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition phosphoinositide degeneration and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   CHRM2
Gene Name:   cholinergic receptor, muscarinic 2
Aliases:   FLJ43243, HM2, MGC120006, MGC120007
RefSeq:   NC_000007.13 NT_007933.15 NG_011846.1
Ensembl:   ENSG00000181072
Entrez:   1129
Chromosome Mapping:   7q31-q35

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