PrimePCR™ Probe Assay: GRIA3, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: GRIA3, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: GRIA3, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039219
Assay Design:   exonic
Chromosome Location:   X:122319727-122319821question
Amplicon Length:   65
Splice Variants Targeted:   ENST00000371266 ENST00000371264 ENST00000371251 ENST00000371256 ENST00000264357 ENST00000542149 ENST00000541091

Gene Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms which may vary in their signal transduction properties. [provided by RefSeq Jul 2008]

Gene Symbol:   GRIA3
Gene Name:   glutamate receptor, ionotrophic, AMPA 3
Aliases:   GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94
RefSeq:   NC_000023.10 NT_011786.16 NG_009377.1
Ensembl:   ENSG00000125675
Entrez:   2892
Chromosome Mapping:   Xq25

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