PrimePCR™ Probe Assay: EDNRA, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: EDNRA, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: EDNRA, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039363
Assay Design:   exonic
Chromosome Location:   4:148457047-148457181question
Amplicon Length:   105
Splice Variants Targeted:   ENST00000511804 ENST00000324300 ENST00000506066 ENST00000358556 ENST00000339690

Gene Information

This gene encodes the receptor for endothelin-1 a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq Oct 2009]

Gene Symbol:   EDNRA
Gene Name:   endothelin receptor type A
Aliases:   ETA, ETAR, ETRA
RefSeq:   NC_000004.11 NT_016354.19 NG_013343.1
Ensembl:   ENSG00000151617
Entrez:   1909
Chromosome Mapping:   4q31.22

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